Jing Liu, MB, PhD
I have broad interests in vascular biology, metabolism, and renal physiology. Prior research experience was dedicated to understanding the roles of lipoproteins in atherosclerosis and aneurysm, microRNA-mediated regulation of vascular remodeling and metabolism, and molecular and cellular mechanisms of renal physiology and blood pressure control. Building on this expertise, my current efforts are devoted to investigating the causal effects of “forever chemicals” per- and polyfluoroalkyl substances (PFAS) in 1) dyslipidemia and macrovascular diseases including atherosclerosis and aneurysm; 2) hypertension and microvascular dysfunction; and 3) renal dysfunction and chronic kidney disease.
Degree(s)
- 2021 MB, Peking University Health Science Center, Beijing, China
- 2015 PhD, Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY
- 2018 Postdoctoral Fellow, University of Iowa, Iowa City, IA
- 2021 Postdoctoral Fellow, Medical College of Wisconsin, Milwaukee, WI
Liu J, Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Sorci-Thomas M, Cassis LA, Daugherty A. Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol. 2015 Aug; 35(8): 1826-34.
Gabani M, Liu J, Ait-Aissa K, Koval O, Kim YR, Castañeda D, Vikram A, Jacobs JS, Grumbach I, Trebak M, Irani K, Kassan M. MiR-204 regulates type 1 IP3R to control vascular smooth muscle cell contractility and blood pressure. Cell Calcium. 2019 Jun; 80: 18-24.
Liu J, Lu H, Moorleghen JJ, Howatt DA, Balakrishnan A, Daugherty A. Hypercholesterolemia accelerates both the initiation and progression of angiotensin II-induced abdominal aortic aneurysms. Ann Vasc Med Res. 2020 Jan; 7(1): 1099.
Cheng Y, Wang D, Wang F, Liu J, Huang B, Baker MA, Yin J, Wu R, Liu X, Regner KR, Usa K, Liu Y, Zhang C, Dong L, Geurts AM, Wang N, Miller SS, He Y, Liang M. Endogenous miR-204 protects the kidney against chronic injury in hypertension and diabetes. J Am Soc Nephrol 2020 Jul;31(7):1539-1554.
Liu J, Liu Y, Wang F, Liang M. miR-204: Molecular Regulation and Role in Cardiovascular and Renal Diseases. Hypertension. 2021 Aug;78(2):270-281.
Liu J, Wu J. The Pathogenesis and Impact of Arterial Stiffening in Hypertension. American Journal of Hypertension. 2024 Mar 15;37(4):241-247.